Spironolactone transsexuals

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Medical Referral Disclaimer The CoE is unable to respond to individual patient requests for medical guidance. Anti-androgen treatments such as spironolactone in doses up to mg daily and cyproterone in doses up to mg daily are effective adjunctive therapies, given in addition to oestrogen to lower testosterone concentrations into the female range. Spironolactone is a weak steroidogenesis inhibitor. The clinical benefits of spironolactone as a diuretic are typically not seen until 2 to 3 days after dosing begins. The hormonal regimens used for transgender women are not standardised across the world table 2partly because of regional differences in the availability of oestrogen and testosterone-lowering preparations, as well as cost considerations and differences in practices between countries and centres. National Center for Biotechnology InformationU. Travis 23 September

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Elks 14 November Conversely, Endocrine Society guidelines recommend monitoring of hormone levels every 3 months. The drawback for this approach is that patients may begin to experience estrogenic side effects as described below. Cardiac Problems in Pregnancy:

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